Epithalon: Research Overview
Epithalon (also spelled Epitalon) is a synthetic tetrapeptide with the sequence Ala-Glu-Asp-Gly. It was developed based on epithalamin, a peptide extract from the pineal gland, by Russian scientist Vladimir Khavinson. Research has focused on its potential relationship to telomerase activity.
Peptide Profile
| Property | Details |
|---|---|
| Full Name | Epithalon / Epitalon |
| Sequence | Ala-Glu-Asp-Gly (AEDG) |
| Amino Acids | 4 (tetrapeptide) |
| Molecular Weight | ~390 g/mol |
| Purity | 99%+ (HPLC verified) |
| Form | Lyophilized powder |
Background
Epithalamin Origin
Epithalon is a synthetic version based on:
Telomerase Connection
Research interest centers on:
Understanding Telomeres
What Are Telomeres?
Telomeres are:
Telomerase Enzyme
Telomerase:
Research Applications
Telomerase Studies
Aging Research
Pineal Research
Reconstitution Protocol
Standard Volumes
| Vial Size | BAC Water | Concentration |
|---|---|---|
| 10mg | 2ml | 5,000mcg/ml |
| 20mg | 4ml | 5,000mcg/ml |
Procedure
Storage Guidelines
Lyophilized
Reconstituted
Physical Properties
Lyophilized:
Reconstituted:
Research Considerations
Assay Methods
Common research approaches:
Controls
Appropriate controls include:
Related Research
| Topic | Connection |
|---|---|
| Telomerase activators | Mechanism comparison |
| Pineal peptides | Related bioregulators |
| Senolytic research | Aging biology overlap |
Conclusion
Epithalon provides researchers with a tool to investigate telomerase biology and cellular aging mechanisms. Its simple tetrapeptide structure and research history support its use in longevity and telomere research applications.
*Epithalon is sold for research purposes only and is not approved for human use.*
Frequently Asked Questions
What is Epithalon's relationship to telomerase?
Epithalon has been studied for its potential to affect telomerase activity, the enzyme that maintains telomere length. Research has examined whether it influences hTERT expression and telomerase function in various cell models.
Is Epithalon natural or synthetic?
Epithalon is a synthetic tetrapeptide. It was designed based on epithalamin, a peptide extract originally derived from bovine pineal glands, but is now produced through chemical synthesis.
Why is Epithalon such a small peptide?
At only 4 amino acids (AEDG), Epithalon is a tetrapeptide. Its small size contributes to stability and ease of synthesis. The specific sequence was identified as the active core of the larger epithalamin extract.
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