Semax
30mg · 99%+ Purity
Description
Semax, an analog of ACTH(4-10), is investigated for its influence on neuroplasticity through BDNF upregulation. This peptide is primarily studied for its potential role in cognitive function research.
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Research & Science
Evidence-based information about this compound
Chemical Properties
CAS Number
80714-61-0
Molecular Formula
C37H51N9O10S
Molecular Weight
813.93 g/mol
Amino Acid Sequence
Met-Glu-His-Phe-Pro-Gly-Pro
Also known as:
SEMAX, ACTH 4-10 analog, Heptapeptide Semax
Semax is a synthetic heptapeptide (seven amino acids) derived from the naturally occurring adrenocorticotropic hormone (ACTH) fragment 4-10. Developed in Russia during the 1980s, Semax has been extensively studied for its cognitive-enhancing and neuroprotective properties.
The peptide consists of the amino acid sequence Met-Glu-His-Phe-Pro-Gly-Pro, which represents a modified fragment of ACTH with enhanced stability and CNS activity. Importantly, Semax lacks the hormonal effects of full ACTH while retaining its neurotrophic properties.
Semax has been approved in Russia for cognitive enhancement and has been the subject of numerous clinical studies examining its effects on brain function, memory, and neuroprotection.
Semax exerts its effects through multiple neurological mechanisms:
- BDNF Enhancement: Increases brain-derived neurotrophic factor (BDNF) expression, crucial for neuroplasticity and learning.
- Neurotrophic Effects: Promotes neuronal survival, growth, and differentiation.
- Dopamine Modulation: Influences dopaminergic system activity in brain regions important for cognition.
- Serotonin Effects: May modulate serotonergic signaling in the brain.
- Neuroprotection: Provides protection against oxidative stress and neurotoxic insults.
Semax has been extensively studied for its cognitive effects:
- Memory Enhancement: Research shows improvements in memory formation and recall in various models.
- Attention: Studies indicate enhanced attention and focus capabilities.
- Learning: Evidence suggests facilitation of learning processes.
- BDNF Expression: Upregulation of BDNF may underlie many cognitive benefits.
The combination of cognitive enhancement with neuroprotective properties makes Semax unique among nootropic peptides.
Semax demonstrates significant neuroprotective properties:
- Oxidative Stress: Protects neurons from oxidative damage.
- Ischemic Protection: Research shows protective effects in models of stroke and ischemia.
- Neuroinflammation: May reduce harmful neuroinflammatory processes.
- Neurodegeneration: Studies suggest potential protective effects against neurodegenerative processes.
These neuroprotective effects complement Semax's cognitive enhancement properties.
Sources:
This information is provided for educational purposes only and is based on published scientific research. This product is intended for research use only.
