Selank
5mg · 99%+ Purity
Description
Selank is a heptapeptide shown to modulate the tuftsin pathway, influencing both cognitive function and immune response. Research applications focus on its potential role in anxiety, learning, and immune system regulation models.
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Research & Science
Evidence-based information about this compound
Chemical Properties
CAS Number
129954-34-3
Molecular Formula
C33H57N11O9
Molecular Weight
751.88 g/mol
Amino Acid Sequence
Thr-Lys-Pro-Arg-Pro-Gly-Pro
Also known as:
SELANK, Selanc, TP-7, Tuftsin-Gly-Pro
Selank is a synthetic heptapeptide derived from the naturally occurring immunomodulatory peptide tuftsin, with an additional Gly-Pro sequence. Developed at the Institute of Molecular Genetics of the Russian Academy of Sciences, Selank has been studied extensively for its anxiolytic, nootropic, and immunomodulatory properties.
The peptide sequence (Thr-Lys-Pro-Arg-Pro-Gly-Pro) represents an enhanced version of tuftsin with improved stability and bioavailability. Unlike many anxiolytic compounds, Selank does not cause sedation or dependence.
Selank has received approval in Russia as a treatment for anxiety and cognitive enhancement, and continues to be an active area of research for its unique combination of neurological and immunological effects.
Selank works through multiple mechanisms affecting both the nervous and immune systems:
- GABAergic Modulation: Influences GABA receptors and transmission, contributing to anxiolytic effects without sedation.
- Serotonin System: Affects serotonergic pathways involved in mood and anxiety regulation.
- BDNF Expression: Increases brain-derived neurotrophic factor levels, supporting neuroplasticity.
- Immunomodulation: Inherits immunostimulatory properties from its parent compound tuftsin.
- Enkephalin Effects: May inhibit enkephalin degradation, affecting opioid signaling.
Selank has been extensively researched for its anti-anxiety effects:
- Anxiety Reduction: Studies demonstrate significant anxiolytic effects comparable to benzodiazepines.
- No Sedation: Unlike many anxiolytics, Selank does not cause drowsiness or sedation.
- No Dependence: Research indicates Selank does not produce dependence or withdrawal effects.
- GABA Enhancement: Effects are partially mediated through GABAergic mechanisms.
This unique profile makes Selank valuable for anxiety research without the drawbacks of conventional anxiolytics.
Beyond anxiolytic effects, Selank demonstrates cognitive-enhancing properties:
- Memory: Research shows improvements in memory formation and retention.
- Learning: Studies indicate enhanced learning capacity.
- Focus: May improve attention and concentration.
- BDNF: Increased BDNF expression supports neuroplasticity and cognitive function.
The combination of anxiolytic and nootropic effects makes Selank unique among peptides.
Sources:
This information is provided for educational purposes only and is based on published scientific research. This product is intended for research use only.
