Ipamorelin
5mg · 99%+ Purity
Description
Ipamorelin is a pentapeptide GH secretagogue exhibiting selective growth hormone-releasing activity. Research indicates potential applications in studies involving bone mineral density and lean body mass.
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Research & Science
Evidence-based information about this compound
Chemical Properties
CAS Number
170851-70-4
Molecular Formula
C38H49N9O5
Molecular Weight
711.85 g/mol
Amino Acid Sequence
Aib-His-D-2-Nal-D-Phe-Lys-NH2
Also known as:
NNC 26-0161, IPAM
Ipamorelin is a synthetic pentapeptide (five amino acids) that acts as a selective growth hormone secretagogue. It belongs to the class of growth hormone releasing peptides (GHRPs) but has a more selective action profile compared to other compounds in this category.
The peptide stimulates the pituitary gland to release growth hormone through activation of the ghrelin/growth hormone secretagogue receptor (GHS-R). Unlike other GHRPs, Ipamorelin is highly selective and does not significantly affect cortisol or prolactin levels.
This selectivity makes Ipamorelin one of the most studied GHRPs for research applications where specific growth hormone effects are desired without broader hormonal influences.
Ipamorelin stimulates growth hormone release through specific mechanisms:
- GHS-R Activation: Binds to the growth hormone secretagogue receptor in the pituitary gland to stimulate GH release.
- Pulsatile Release: Promotes natural pulsatile growth hormone release patterns rather than constant elevation.
- Selective Action: Does not significantly increase cortisol, prolactin, or other hormones.
- Dose-Dependent: Growth hormone release increases proportionally with dose up to saturation.
- Synergy Potential: May work synergistically with GHRH analogs like CJC-1295.
Ipamorelin's effects on growth hormone have been well characterized:
- Robust GH Release: Studies show Ipamorelin produces significant increases in growth hormone levels.
- Selectivity: Research demonstrates minimal effects on cortisol, prolactin, and other hormones unlike other GHRPs.
- Pulsatile Pattern: Maintains natural growth hormone release patterns.
- Dose Response: Clear dose-dependent relationship in growth hormone release.
This selective action profile makes Ipamorelin valuable for research requiring specific growth hormone effects.
This information is provided for educational purposes only and is based on published scientific research. This product is intended for research use only.
